Apoptosis of mural granulosa cells is increased in women with diminished ovarian reserve

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Ovarian reserve status in young women is associated with altered gene expression in membrana granulosa cells.

Diminished ovarian reserve (DOR) is a challenging diagnosis of infertility, as there are currently no tests to predict who may become affected with this condition, or at what age. We designed the present study to compare the gene expression profile of membrana granulosa cells from young women affected with DOR with those from egg donors of similar age and to determine if distinct genetic patter...

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ژورنال

عنوان ژورنال: Journal of Assisted Reproduction and Genetics

سال: 2019

ISSN: 1058-0468,1573-7330

DOI: 10.1007/s10815-019-01446-5